Digging Deeper with Allogeneic Transplantation in Multiple Myeloma
نویسندگان
چکیده
منابع مشابه
Allogeneic transplantation in multiple myeloma.
Allogeneic hematopoietic stem cell transplantation in multiple myeloma has been performed since the 1980th, but is still a controversial treatment modality. The aim is to cure the disease and the rational is to eradicate myeloma cells by the dual effect of high dose myeloablative treatment, and the immune reaction against the myeloma cells by the graft (graft versus myeloma =GVM). At the same t...
متن کاملAllogeneic Hematopoetic Cell Transplantation in Multiple Myeloma
The improvement in the survival of multiple myeloma patients has been attributed to autol‐ ogous stem cell transplantation (ASCT) after induction with novel agents [1,2]. Nevertheless, ASCT has not been considered to have a curative potential, maintenance treatment seems to be one of the solutions to decrease the high relapse rates after ASCT [3]. Therefore, allogeneic stem cell transplantation...
متن کاملMultiple Myeloma: Role of Allogeneic Transplantation
In this article, Pandit and Vesole present a focused overview of allogeneic transplantation for multiple myeloma. Additionally, this article addresses the challenges of allogeneic transplantation, including continued relapse and treatment-related toxicity and mortality. Shortcomings of Current Therapy Multiple myeloma remains an incurable disease despite advances in systemic therapy and support...
متن کاملMultiple Myeloma: Role of Allogeneic Transplantation
In this article, Pandit and Vesole present a focused overview of allogeneic transplantation for multiple myeloma. Additionally, this article addresses the challenges of allogeneic transplantation, including continued relapse and treatment-related toxicity and mortality. Shortcomings of Current Therapy Multiple myeloma remains an incurable disease despite advances in systemic therapy and support...
متن کاملMultiple myeloma: role of allogeneic transplantation.
An estimated 14,600 new cases of multiple myeloma will be diagnosed in the United States in 2002. Multiple myeloma remains an incurable disease despite significant improvements in complete response rates and overall survival through the use of autologous stem cell transplantation. Allogeneic transplantation offers the advantage of a tumor-free graft and a graft-vs-myeloma effect but has been as...
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ژورنال
عنوان ژورنال: Biology of Blood and Marrow Transplantation
سال: 2013
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2012.12.020